Life Biosciences Appoints Sharon Rosenzweig-Lipson, PhD as Chief Scientific Officer
Dr. Rosenzweig-Lipson brings decades of experience in R&D strategy and clinical development as Life Biosciences advances therapeutics that target the biology of aging
BOSTON, February 13, 2023 – Life Biosciences, a pioneering life sciences company developing therapeutics that target the biology of aging, today announced the appointment of Sharon Rosenzweig-Lipson, PhD as Chief Scientific Officer. At Life Biosciences, she will be responsible for leading the company’s scientific research and development efforts built on the epigenetic reprogramming science of Dr. David Sinclair and the chaperone-mediated autophagy discoveries of Dr. Ana Maria Cuervo.
“Dr. Rosenzweig-Lipson brings great scientific and strategic leadership to Life Biosciences,” said Jerry McLaughlin, Chief Executive Officer at Life Biosciences. “Sharon has been serving as a consultant to Life since early 2021 and has helped to create strong processes to accelerate our drug discovery and development. Her impressive background and accomplishments in both preclinical and clinical development will continue to be invaluable to us as we progress our therapies toward the clinic. It is a pleasure to officially welcome her to the team.”
“I am thrilled to be joining Life Biosciences to revolutionize the treatment of a wide-range of age-related disorders,” said Dr. Rosenzweig-Lipson. “I look forward to collaborating with the strong mission-driven team at Life Biosciences and its outstanding scientific collaborators.”
Dr. Rosenzweig-Lipson holds significant expertise in screening strategies, in vivo models, translation, and clinical development strategy with more than three decades of experience developing compounds for psychiatric and neurologic indications in the pharmaceutical industry and in biotech. Her career in big pharma includes American Cyanamid, American Home Products, Wyeth, and Pfizer. Most recently, as head of R&D, Dr. Rosenzweig-Lipson led the clinical development of AgeneBio’s lead asset through Phase 2B trials as well as the company’s preclinical development programs. Dr. Rosenzweig-Lipson earned her BA in the biological basis of behavior from the University of Pennsylvania and her PhD in behavioral neuroscience from Harvard University.
About Life Biosciences
Life Biosciences is a private biotechnology company dedicated to discovering and developing novel therapies to improve the lives of people as they age. The company is focusing on two platforms targeting key mechanisms underlying aging biology: epigenetic reprogramming to restore cellular function to a more youthful state and chaperone-mediated autophagy to reverse the age-related decline in the body’s ability to recycle unwanted proteins. Therapies developed within these platforms have the potential to prevent, treat, and/or reverse multiple aging-related diseases. For more information, please visit www.lifebiosciences.com.
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Life Biosciences CEO Jerry McLaughlin to Speak at Roadmap to Healthy Longevity International Summit
BOSTON, February 9, 2023 — Life Biosciences, a pioneering biotech company developing therapeutics that target the biology of aging, today announced that Jerry McLaughlin, Chief Executive Officer, will speak at the Roadmap to Healthy Longevity: Enabling Healthier, Longer Lives in the GCC conference February 19, 2023, in Riyadh, Saudi Arabia. McLaughlin will participate on a panel entitled “Meet the Healthy Longevity Innovators.”
“Our scientific team at Life Biosciences is at the cutting edge of developing novel therapies based on exciting advances in age-related science,” said McLaughlin. “I’m proud to speak at this important international conference to discuss developments in the bourgeoning healthspan space that are rooted in innovative science as well as to share more about Life’s scientific progress to date and its robust pipeline.”
About the Conference
Jointly organized by the US National Academy of Medicine (NAM), Hevolution Foundation, and the King Abdullah International Medical Research Center (KAIMRC), the event will gather leaders from across the longevity ecosystem to discuss the state of longevity and healthy lifespan in the Gulf Region and an envisioned world with healthy longevity by 2050.
About Life Biosciences
Life Biosciences is a private biotechnology company dedicated to discovering and developing novel therapies to improve the lives of people as they age. The company is focusing on two platforms targeting key mechanisms underlying aging biology: epigenetic reprogramming to restore cellular function to a more youthful state and chaperone-mediated autophagy to reverse the age-related decline in the body’s ability to recycle unwanted proteins. Therapies developed within these platforms have the potential to prevent, treat, and/or reverse multiple aging-related diseases. For more information, please visit www.lifebiosciences.com.
Life Biosciences to Present at Longevity Leaders World Congress 2022
BOSTON, April 14, 2022 — Life Biosciences, a pioneering life sciences company developing therapeutics that target the biology of aging, today announced that Jerry McLaughlin, Chief Executive Officer, will speak at the fourth annual Longevity Leaders World Congress being held on April 26-27, 2022, in London, UK.
Mr. McLaughlin will deliver a presentation on April 26 at 11:10 BST titled, “Targeting Mechanisms Underlying the Biology of Aging to Treat and Reverse Disease.”
“Life Biosciences is truly at the forefront of developing novel therapies based on exciting advances in age-related science,” says Mr. McLaughlin. “I’m delighted to have the opportunity to share more about our work and progress here at Life Biosciences and discuss ways to work with pioneers in the field to move our industry forward.”
The Longevity Leaders World Congress, hosted by LSX, brings the world’s most prominent regenerative medicine and longevity scientists together, presenting the new research, responsible drug development, novel therapies, and commercialization to target age-related diseases. Those interested in attending the conference may register here.
About Life Biosciences
Life Biosciences is a private biotechnology company dedicated to discovering and developing novel therapies to improve the lives of people as they age. The company is focusing on three platforms targeting key mechanisms underlying aging biology: mitochondrial uncoupling, chaperone-mediated autophagy, and epigenetic reprogramming. Therapies developed within each platform have the potential to prevent, treat, and/or reverse multiple aging-related diseases. For more information, please visit www.lifebiosciences.com.
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Investor Relations
Bill Sullivan
IR@lifebiosciences.com
Life Biosciences, Leading Developer of Therapeutics for Aging-Related Diseases, Completes $82 Million Series C Financing Round
Announces Bill Sullivan as Chief Financial Officer
BOSTON, Jan. 5, 2022 — Life Biosciences, a pioneering life sciences company developing therapeutics that target the biology of aging, today announced the completion of a Series C financing of $82 million led by Alpha Wave Ventures. Senior management and founders invested in the Series C financing alongside longevity-oriented funds, seasoned investors, and experienced biotechnology scientists/entrepreneurs. Since its founding, Life Biosciences has raised over $158 million.
“Our three platforms are based on seminal research demonstrating that aging biology can be modified therapeutically. The Series C funding enables us to accelerate development of our innovative therapies for multiple aging-related conditions, and we expect to initiate first-in-human studies for our first drug candidate possibly as early as the end of 2022,” said Chief Executive Officer Jerry McLaughlin. “We appreciate the support of both our new and existing investors as we advance the company to its next stage of development. Life Biosciences’ experienced management team is committed to bringing potentially pioneering science to the service of humanity.”
Proceeds from the Series C financing will be used to accelerate research and development activities in the company’s three platforms that target fundamental biological mechanisms contributing to aging. The mitochondrial uncoupling platform is developing oral small molecules that are designed to increase metabolic rate and decrease fat accumulation in models of obesity and NASH. The chaperone-mediated autophagy (CMA) platform is developing oral small molecules that are designed to activate CMA and thereby remove unwanted proteins that accumulate during aging and contribute to multiple aging-related diseases including neurodegenerative diseases. The epigenetic reprogramming platform is developing therapies that are designed to induce the expression of three Yamanaka factors to reprogram the epigenome of cells to a younger state and thereby restore cellular function across a wide range of diseases such as glaucoma.
Commenting on the investment, Alpha Wave Global Chairman Rick Gerson added, “We are impressed by the groundbreaking science that has been published in leading and recently peer-reviewed journals like Nature and Cell by the company’s co-founder and director David Sinclair and other founder scientists such as Dr. Ana Maria Cuervo. Their foundational science could revolutionize how we develop therapies for aging-related conditions. We are excited to invest in this emerging field and believe that Life Biosciences’ experienced management team and exceptional science has the potential to unlock a new wave of therapies across their multiple platforms.”
In addition, Life Biosciences announces the appointment of Bill Sullivan as Chief Financial Officer. Bill brings more than 25 years of experience in corporate finance, strategic transactions, fundraising, and investor relations. He served as Chief Financial Officer and Treasurer at Applied Genetic Technologies Corporation, a publicly traded gene therapy company, where he led multiple financings and core business and finance functions. Prior to AGTC, he worked at Merrimack Pharmaceuticals, Inc. for ten years and held a variety of important leadership positions including Chief Financial Officer.
“It’s an honor to join the Life Biosciences team as the company pursues tremendous growth opportunities where aging biology has a clear link to disease pathogenesis,” said Mr. Sullivan. “I’m energized by both the people and strong science at the company and look forward to working together with the management team to drive the next phase of growth.”
“I couldn’t be more delighted by the progress made by the Life Biosciences’ team under Jerry’s leadership to sharpen its focus on developing therapeutics on a platform-oriented approach. In my opinion, Life Biosciences is on the cusp of revolutionizing medicine for aging-related diseases globally,” said Executive Chairman Dr. Mehmood Khan.
About Life Biosciences
Life Biosciences is a private biotechnology company dedicated to discovering and developing novel therapies to improve the lives of people as they age. The company is focusing on three platforms targeting key mechanisms underlying aging biology: mitochondrial uncoupling, chaperone-mediated autophagy, and epigenetic reprogramming. Therapies developed within each platform have the potential to prevent, treat, and/or reverse multiple aging-related diseases. For more information, please visit www.lifebiosciences.com.
About Alpha Wave Global
Alpha Wave is a global investment company with offices in New York, Miami, London, Abu Dhabi, Tel Aviv, and Bangalore. Its flagship global venture and growth fund, Alpha Wave Ventures, aims to invest in best-in-class venture and growth-stage companies and endeavors to be helpful long-term partners to the founders and management teams. Alpha Wave manages a variety of investment partnerships that cover a number of asset classes, themes, and geographies. For more information, please visit www.alphawaveglobal.com.
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Maggie Farrand
media@lifebiosciences.com
Life Biosciences Receives Translational Research Funding from Alzheimer’s Drug Discovery Foundation
BOSTON, Sept. 28, 2021 — Life Biosciences, a pioneering life sciences company developing therapeutics that target the biology of aging, today announced translational research funding from the Alzheimer’s Drug Discovery Foundation (ADDF) to support the development of chaperone-mediated autophagy (CMA) activators for the treatment of Alzheimer’s disease and other neurodegenerative diseases.
Chaperone-mediated autophagy removes unwanted soluble proteins from cells. CMA activity declines with age due in part to decreased expression of LAMP2A, a key protein regulating CMA activity. The age-related decline of CMA leads to an accumulation of insoluble proteins that disrupt cellular function in age-related diseases such as Alzheimer’s disease.
In groundbreaking work published in the peer-reviewed journal Cell in April 2021, Professor at the Albert Einstein College of Medicine and Life Biosciences founder scientist Ana Maria Cuervo, MD, PhD demonstrated the benefit of the CMA-activator platform in two mouse models of Alzheimer’s disease. In both models, oral doses of CMA-activator compounds led to improvements in memory, depression, and anxiety. Life Biosciences has an exclusive license from Albert Einstein College of Medicine for this underlying technology and will continue this research by evaluating CMA-activator compounds for key early attributes needed in Alzheimer’s disease drug development.
“We are pleased to have received this translational research funding from the ADDF, which further validates the potential of our CMA platform to treat devastating diseases such as Alzheimer’s,” said Jerry McLaughlin, Chief Executive Officer of Life Biosciences. “Our preclinical work to date has demonstrated that CMA activation may be a viable therapeutic strategy in halting the progression of age-related neurodegenerative disorders and ultimately increase healthy human lifespan. We look forward to advancing this platform towards the clinic with the support of the ADDF.”
“Life Biosciences’ innovative pathway holds exciting promise for the potential treatment and prevention of Alzheimer’s disease,” said Howard Fillit, MD, Founding Executive Director and Chief Science Officer of the ADDF. “After substantial scientific review, we believe that CMA could offer a unique approach to Alzheimer’s disease, and we look forward to partnering with Life Biosciences as it advances its important research towards the clinic.”
About Life Biosciences
Life Biosciences is a private biotechnology company dedicated to developing novel therapies to extend healthy human lifespan. The Company is focusing on three platforms targeting key mechanisms underlying aging biology: mitochondrial uncoupling, chaperone-mediated autophagy, and epigenetic reprogramming. Therapies developed within each platform have the potential to prevent, treat, and/or reverse multiple aging-related diseases. For more information, please visit www.lifebiosciences.com.
About the Alzheimer’s Drug Discovery Foundation
Founded in 1998 by Leonard A. and Ronald S. Lauder, the Alzheimer’s Drug Discovery Foundation is dedicated to rapidly accelerating the discovery of drugs to prevent, treat and cure Alzheimer’s disease. The ADDF is the only public charity solely focused on funding the development of drugs for Alzheimer’s and related dementias, employing a venture philanthropy model to support research in academia and the biotech industry. Through the generosity of its donors, the ADDF has awarded more than $168 million to fund over 650 Alzheimer’s drug discovery and biomarker programs and clinical trials in 19 countries. To learn more, please visit: http://www.alzdiscovery.org/.
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Maggie Farrand
media@lifebiosciences.com
Life Biosciences Appoints Seasoned Biopharma Executive Jerry McLaughlin as CEO
Dr. Mehmood Khan to remain Executive Chairman
BOSTON, July 1, 2021 — Life Biosciences, a pioneering life sciences company targeting the biology of aging, today announced that the Company’s Board of Directors has appointed Jerry McLaughlin as Chief Executive Officer and a member of the Board. Dr. Mehmood Khan will serve as Executive Chairman of the Board.
“I welcome Jerry to the Life Biosciences team at this exciting time for the company,” said Life Biosciences co-founder and Board member David Sinclair, PhD, AO. “Jerry’s extensive experience leading both public and private companies through clinical development and financing will be an invaluable asset as we advance our multiple leading programs. I would also like to thank Dr. Khan for leading Life Biosciences and achieving important milestones over the past few years, including progressing our three platforms toward the clinic. Mehmood’s continued guidance as Executive Chairman, along with Jerry’s stewardship as CEO, will position Life Biosciences for lasting success.”
“It has been a privilege to serve as Life Biosciences’ CEO, and I am proud of the work we have accomplished together,” said Dr. Khan. “With Jerry’s strong track record of operational excellence, innovation, and delivering results, I am confident he is the ideal person to lead Life Biosciences through its next pivotal phase. I look forward to working with him as Executive Chairman.”
Mr. McLaughlin has over 30 years of experience in the biopharmaceutical industry and has been involved in the discovery, clinical development, and global commercialization of more than a dozen FDA-approved drugs with multiple successful exits. Most recently, he was President and CEO for Neos Therapeutics, Inc., a commercial stage pharmaceutical company. Before that, Mr. McLaughlin served as President and CEO of AgeneBio, Inc., a clinical-stage private biopharma company developing therapies for neurological and psychiatric diseases. Earlier, he held the role of Senior Vice President & Chief Commercial Officer at NuPathe Inc., acquired by Teva Pharmaceuticals in 2014. Mr. McLaughlin began his career at Merck and was extensively involved in multiple blockbuster product launches. He holds a BA in economics from Dickinson College and an MBA from the Villanova School of Business.
“I am thrilled to join Life Biosciences as the company works to advance its first programs toward the clinic,” said Mr. McLaughlin. “Having led companies for over a decade that address neurological and psychological conditions and deficits, I am well versed with the negative impacts of aging on the brain and body. Life Biosciences’ groundbreaking work to address and treat the underlying biology of aging has the potential to lead the next generation of therapies for a growing population that faces increasing challenges from diseases that correlate tightly with growing older.”
Dr. Khan will become CEO at a newly founded global non-profit organization focused on funding research on therapies that address aging biology and extend human healthspan. Dr. Khan’s new role is complementary to Life Biosciences’ research and development work, and he will continue to support the Company as Executive Chairman. Additional details relating to Dr. Khan’s new role will be announced later this year.
About Life Biosciences
Life Biosciences is a private biotechnology company dedicated to developing novel therapies to extend healthy human lifespan. The Company is focusing on three platforms targeting key mechanisms underlying aging biology: mitochondrial uncoupling, chaperone-mediated autophagy, and epigenetic reprogramming. Therapies developed within each platform have the potential to prevent, treat, and/or reverse multiple aging-related diseases. For more information, please visit www.lifebiosciences.com.
Media Contact
Maggie Farrand
media@lifebiosciences.com
Life Biosciences Announces Publication in Cell Demonstrating Therapeutic Benefit of Chaperone-Mediated Autophagy Activators in Alzheimer’s Disease Models
BOSTON, April 22, 2021 — Life Biosciences, a pioneering life sciences company targeting the biology of aging, today announced the publication of preclinical research demonstrating clinical benefit of its chaperone-mediated autophagy activator platform in mice models of Alzheimer’s disease. The article, titled “Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome“ by Bourdenx et al., was published online in the peer-reviewed journal Cell on April 22, 2021.
Chaperone-mediated autophagy (CMA) controls the levels of soluble proteins in cells. It has been proposed that the age-related decline of CMA leads to an increased concentration of insoluble proteins that may play a role in the pathogenesis of neurodegenerative diseases such as Alzheimer’s disease. This study demonstrated that the upregulation of CMA with one of Life Biosciences’ tool oral compounds significantly improved neurologic function and decreased the accumulation of insoluble protein aggregates in two different mouse models of Alzheimer’s disease, even after the onset of neurologic dysfunction.
“The publication of this preclinical study validates our CMA platform and demonstrates that an age-related decline in CMA activity may contribute to the pathogenesis of Alzheimer’s disease,” said Joan Mannick, MD, Head of Research and Development at Life Biosciences. “As we look ahead, we anticipate advancing our platform of CMA activating candidates towards the clinic for the potential treatment of aging-related diseases including neurodegenerative diseases.”
Ana Maria Cuervo, MD, PhD, a Life Biosciences founder scientist and Professor and Co-Director of the Institute for Aging Research at the Albert Einstein College of Medicine, commented, “The results of this study identify a direct contribution of CMA to the maintenance of the neuronal proteome in vivo in physiological and pathological conditions. Additionally, this paper provides evidence of the potential value of CMA activation as a therapeutic strategy for age-related neurodegenerative disorders. We look forward to progressing the clinical development of our compounds that activate CMA and believe that this new approach has the potential to prevent the buildup of insoluble proteins that underlie neurologic dysfunction.”
Life Biosciences has in-licensed the intellectual property related to targeting of CMA from Albert Einstein College of Medicine.
About Life Biosciences
Life Biosciences is a private biotechnology company dedicated to developing novel therapies to extend healthy human lifespan. The Company is focusing on three platforms targeting key mechanisms underlying aging biology: mitochondrial uncoupling, chaperone-mediated autophagy, and epigenetic reprogramming. Therapies developed within each platform have the potential to prevent, treat, and/or reverse multiple aging-related diseases. For more information, please visit www.lifebiosciences.com.
Media Contact
Maggie Farrand
media@lifebiosciences.com
Investor Relations Contact
Stern Investor Relations
Alexander Lobo
alex.lobo@sternir.com
Life Biosciences to Present at 5th Stanford Drug Discovery Symposium
BOSTON, April 14, 2021 — Life Biosciences, a pioneering life sciences company targeting the biology of aging, today announced that Joan Mannick, MD, Head of Research and Development, will participate in the 5th Stanford Drug Discovery Symposium (SDDS 2021) being held virtually on April 19-20, 2021.
5th Stanford Drug Discovery Symposium (SDDS 2021)
Session VIII: Discovery Research II
Presentation: Targeting the Biology of Aging to Prevent or Treat Aging-related Diseases
Moderators: Marc Tessier-Lavigne, PhD, and Kuldev Singh, MD
Tuesday, April 20, 2021
2:45pm ET / 11:45am PT
The Stanford Drug Discovery Symposium takes advantage of the collective experience and expertise of participants to cover a broad range of policy, research, and venture topics. This symposium provides an invaluable forum for interdisciplinary exchange at the forefront of drug research. Those interested in attending the virtual symposium may register here.
About Life Biosciences
Life Biosciences is a private biotechnology company dedicated to developing novel therapies to extend healthy human lifespan. The Company is focusing on three platforms targeting key mechanisms underlying aging biology: mitochondrial uncoupling, chaperone-mediated autophagy, and epigenetic reprogramming. Therapies developed within each platform have the potential to prevent, treat, and/or reverse multiple aging-related diseases. For more information, please visit www.lifebiosciences.com.
Media Contact
Maggie Farrand
media@lifebiosciences.com
Investor Relations Contact
Stern Investor Relations
Alexander Lobo
alex.lobo@sternir.com
Life Biosciences Announces Pioneering Research in Nature Describing New Mechanisms for Reversing Age-Related Disease
BOSTON, Feb. 18, 2021 — Life Biosciences, a pioneering life sciences company targeting the biology of aging, has in-licensed intellectual property related to scientific findings recently described in two publications in the journal Nature. The publications, based on research conducted in animal models, report that therapies targeting the biology of aging have the potential to not only slow the progression but also to reverse aging-related disease. Life Biosciences intends to develop new therapies for aging-related conditions.
“These two studies open a new frontier in biotechnology and medicine,” says Mehmood Khan, MD, Chief Executive Officer of Life Biosciences. “They pave the way for the development of groundbreaking treatments to restore the function of aging organ systems and thereby allow people to live healthier longer.”
The first article reports on studies led by David Sinclair, PhD, AO, a co-founder of Life Biosciences, and his colleagues at Harvard Medical School, Massachusetts Eye and Ear, Massachusetts General Hospital, University of California Los Angeles, and Yale School of Medicine. In this study, conducted in cell lines and in animal models, the researchers rejuvenated damaged or aged cells in the eye with a gene therapy that induced expression of three of the Yamanaka factor proteins. This gene therapy allowed nerves in the eye to regrow after injury and safely restored vision, both in old mice and in a mouse model of glaucoma. The full article, titled “Reprogramming to recover youthful epigenetic information and restore vision,” is available through the Nature website (https://doi.org/10.1038/s41586-020-2975-4). The license held by Life Biosciences subsidiary, Iduna Therapeutics, from Harvard University covers a patented gene therapy system for the expression of specific factors known to induce pluripotency and rejuvenation.
“The study shows for the first time that it may be possible to wind the clock back in complex tissues to restore youthful biological functions such as vision,” said Sinclair. “It is promising research in terms of how we address aging-related diseases, including diseases such as glaucoma, which affect many patients later in life.”
The second article reports on studies led by Ana Maria Cuervo, MD, PhD, a Life Biosciences founder scientist and member of the National Academy of Sciences. Dr. Cuervo and her colleagues at Albert Einstein College of Medicine and the University of Colorado Denver reported that the diminished ability of old mouse and human hematopoietic stem cells (HSCs) to produce new blood cells is correlated with a decline in a process called chaperone-mediated autophagy (CMA). CMA breaks down unwanted proteins in cells and recycles them into nutrients. When CMA was activated in the hematopoietic stem cells of geriatric mice, either genetically or by treatment with a small molecule, the old stem cells regained the capacity of young stem cells to generate new blood cells. The findings indicate that therapies that activate CMA have the potential to restore the function of aging hematopoietic stem cells and improve immune function. Life Biosciences has in-licensed the intellectual property related to targeting of CMA from Albert Einstein College of Medicine. The full article, titled “Chaperone-mediated autophagy sustains haematopoietic stem-cell function,” is available through the Nature website (https://doi.org/10.1038/s41586-020-03129-z).
“By activating chaperone-mediated autophagy, we are able to restore the functionality of hematopoietic stem cells in both old mice and older humans, which has very important therapeutic implications,” said Cuervo. “We are looking forward to further investigating how we can put chaperone-mediated autophagy to use in restoring the vitality of aging cells in older people.”
About Life Biosciences
Founded in 2017 and headquartered in Boston, Life Biosciences brings scientists together from the world’s preeminent research and academic institutions into a discovery, development, and commercialization ecosystem dedicated to extending the healthy human lifespan. We are pursuing clinical therapies across multiple molecular pathways that regulate the biology of aging. This means our therapies each have the potential to address multiple age-related diseases that impact longevity far upstream from conventional medicine. www.lifebiosciences.com
Media Contact
Maggie Farrand
media@lifebiosciences.com
Life Biosciences Appoints Joan Mannick, MD, to Lead its Research and Development
Expert on aging will focus on R&D pipeline and clinical preparations
BOSTON, Feb. 1, 2021 —Life Biosciences, a pioneering life sciences company targeting aging biology, announced today the appointment of Joan Mannick, MD, as Head of Research and Development. With more than 20 years of experience, Dr. Mannick will direct and manage the company’s portfolio of R&D operations.
“We are excited to welcome Dr. Mannick as our Head of R&D,” said Mehmood Khan, MD, Chief Executive Officer, Life Biosciences. “Joan’s expertise aligns so closely with our vision of pursuing therapies for age-related diseases by targeting the biological causes of aging, and I’m confident she will help us take Life Biosciences to the next level.”
Dr. Mannick joins Life Biosciences from Adicet Bio, formerly resTORbio, where she served as Co-Founder and Chief Medical Officer and led R&D efforts. Before that, she served as Executive Director of the New Indications Discovery Unit at Novartis Institutes of Biomedical Research, where she led their clinical-stage program targeting aging biology as a new way to treat aging-related conditions. Prior to joining Novartis, Dr. Mannick was Medical Director at Genzyme Corporation working in multiple therapeutic areas including leading an investigator-sponsored program for an early stage oncology product. She has served as faculty member at Harvard Medical School and University of Massachusetts Medical School. She received her AB from Harvard College and MD from Harvard Medical School. She completed her residency at Brigham and Women’s Hospital, followed by an infectious diseases fellowship as part of the Harvard Combined Infectious Diseases Program.
“I am thrilled to join Life Biosciences because I think it has in-licensed the most exciting programs of any company in the aging field,” said Dr. Mannick. “With truly inspiring science and an incredibly talented team of world-leading researchers, Life Biosciences has huge potential to change the course of aging and age-related diseases, and I am honored to now be a part of it.”
About Life Biosciences
Founded in 2017 and headquartered in Boston, Life Biosciences brings scientists together from the world’s preeminent research and academic institutions into a discovery, development, and commercialization ecosystem dedicated to extending the healthy human lifespan. We are pursuing clinical therapies across multiple molecular pathways that regulate the biology of aging. This means our therapies each have the potential to address multiple age-related diseases that impact longevity far upstream from conventional medicine. www.lifebiosciences.com
Media Contact
Maggie Farrand
media@lifebiosciences.com